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Starch, dietary fiber, and BioBran are classified as polysaccharides. Starch is digested by saliva, pancreatic juice, and intestinal juice, and is absorbed in the small intestine as glucose. Dietary fiber is not digested, and is excreted unchanged. BioBran is known to be partly absorbed directly in the digestive tract, entering the blood stream. BioBran activates the Natural Killer Cells, T cells, B cells, and macrophages, either directly in the blood, or indirectly via the Peyer’s patch of the ileum, so plays an important role in immunomodulation (immunostimulation, anti-inflammation, anti-allergy and antioxidation processes). Overall, BioBran is considered to enhance the body’s natural healing abilities, alleviate the adverse drug reactions of chemotherapeutic agents, and improve quality of life.

BioBran is produced from rice bran. Hemicellulose B, a type of soluble dietary fiber contained in rice bran, is a polysaccharide with a complex structure consisting of arabinose and xylose. As it is, Hemicellulose B exerts no immunostimulatory effects.   However, by reacting hemicellulose B with carbohydrate-hydrolyzing enzymes obtained from shiitake mushroom mycelia, it exerts immunomodulatory effects. This product, BioBran, is a unique functional food ingredient developed by Daiwa, which focuses on traditional Japanese food and fermentation technology.